Fig. 4: Transient binding of T8-Lymphocytes to Dendritic Cells

As naive T8-lymphocytes migrate through the cortical region of lymph nodes, they use surface cell adhesion molecules such as LFA-1 and CD2 to bind transiently to corresponding receptors such as ICAM-1, ICAM-2 and CD58 on the surface of dentritic cells. This transient binding allows time for the TCRs on the T8-lymphocyte to sample large numbers of MHC-I/peptide complexes on the antigen-presenting dendritic cells.

Illustration of Transient binding of T8-Lymphocytes to Dendritic Cells .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html.

Creative Commons License

Last updated: August, 2019
Please send comments and inquiries to Dr. Gary Kaiser